Imipramine {antidepressant drug}| can relieve depression by prolonging time noradrenaline and serotonin stay in synapses, by inhibiting membrane epinephrine, norepinephrine, dopamine, and serotonin transport back into cells and preventing pre-synaptic neuron re-uptake into vesicles. Iproniazid (Niamid) inhibits monoamine oxidase to prevent noradrenaline and serotonin breakdown.
types
Selective serotonin re-uptake inhibitors, such as Prozac, affect only serotonin. Selective noradrenaline re-uptake inhibitors, such as Strattera, affect only noradrenaline. Tricyclic antidepressants, such as Elavil, affect both.
Monoamine oxidase inhibitors, such as Nardil, prevent enzymes from reacting with noradrenaline and serotonin. Wellbutrin and Serzone affect related reactions.
effects
People are not likely to misuse antidepressant drugs.
biology
Tryptophan is a serotonin precursor.
Drugs {clozapine} (Clozaril) {atypical antipsychotic} can weakly block dopamine receptors and affect glutamine receptors.
Drugs {buspiron} can excite serotonin-IA receptors.
Drugs {dopamine antagonist} can compete for dopamine receptor but have no metabolic effect themselves.
Aminated indoles {indoleamine} {indolamine} include serotonin, LSD, and psilocybin and affect serotonin system {5-HT system}.
Oxidases {monoamine oxidase}| (MAO) {MAO-A gene} can inactivate catecholamines, such as norepinephrine, dopamine, and serotonin. Drugs {monoamine oxidase inhibitor} {MAO inhibitor} can inhibit monoamine oxidase and keep monoamine concentration high. Monoamine oxidase inhibitors can control aggression.
Monoamine oxidase inhibitors {tricyclic antidepressant} can treat endogenous depression.
4-Medicine-Drug-Kinds-Mental Illness
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Date Modified: 2022.0225